Wellness Care • Editorial Library

Longevity Science.

A library curated by our medical team covering the global state of the art in longevity medicine. Mechanisms, evidence, ongoing clinical trials, and regulatory status for each modality. No promises, no aspirational language — only what the science actually shows today, organized so you can understand, not so you can buy.

Built on the same principle we apply in clinic: education first, individualized recommendation second. After you read, if you want to understand how it applies to your case, schedule an evaluation consultation with biomarkers.

Three clinical pillars: functional, biological, regenerative

Before the modality categories — peptides, biomarkers, TPE — comes the clinical model that organizes them. Wellness Care operates on three philosophical pillars: functional medicine (identify root cause), biological medicine (restore intrinsic regulation), and regenerative medicine (reactivate the biology of repair). Each one operationally differs from conventional medicine — it does not replace it, it complements it.

The 19 modality categories — peptides, biomarkers, exosomes, MSC, TPE — always apply within one or more of these three clinical pillars.
The three clinical pillars

The model before the modalities

Each pillar has its own philosophical page with comparison vs conventional medicine, diagnostic biomarkers, and indexed evidence.

Clinical pillar

Functional Medicine

Identifies the root cause, does not suppress the symptom. ATM model (Antecedents, Triggers, Mediators) from the Institute for Functional Medicine. Validated at Cleveland Clinic — JAMA Network Open 2019.

Explore pillar → Clinical pillar

Biological Medicine

Restores the body's intrinsic regulation — autonomic system, neuroendocrine axis, extracellular matrix. HRV, vagal tone, polyvagal. Indexed evidence in Nature, Frontiers in Public Health, FDA.

Explore pillar → Clinical pillar

Regenerative Medicine

Reactivates the biology of repair rather than replacing tissue. Mesenchymal stem cells, exosomes, paracrine signaling. Case-by-case indication under applicable INVIMA framework.

Explore pillar →
Available

Advanced Biomarkers

Biological age (DunedinPACE, GlycanAge), telomeres, DNA methylation, microbiome, inflammatory markers, advanced lipidomics. How they're measured and what they mean.

Explore → Available

Therapeutic Plasma Exchange

TPE mechanisms, Buck Institute evidence (Fuentealba 2025), longevity applications, Long COVID, and elimination of persistent synthetic chemicals.

Explore → Available

Long COVID & Post-Viral Fatigue

Treatment of post-COVID syndrome, chronic post-viral fatigue, brain fog, POTS, and autonomic dysfunction with Therapeutic Plasma Exchange. Indexed clinical evidence — Achleitner 2023, Cunningham, post-COVID POTS.

Explore → Available

Therapeutic Peptides

The global state of the art organized in three tiers: FDA-approved with longevity relevance, in active clinical research, and preliminary evidence / international use.

Explore → Available

Regenerative Medicine

Mesenchymal stem cells and exosomes: what they are, hypoxia vs normoxia culture, mechanisms of action, clinical evidence, and global regulatory status.

Explore → Available

Joint & Spine Regeneration

The science of repairing damaged cartilage. MSC, exosomes, TPE and IV therapy applied to osteoarthritis, disc herniation, sports injuries, and chronic spine pain. 500+ clinical trials.

Explore → Available

Brain, Cognition & Neuroinflammation

ExBrain (nebulized exosomes), Cerebrolysin, Semax, BPC-157, IV NAD+. Evidence on chronic neuroinflammation, mild cognitive impairment, brain fog, and cognitive performance optimization.

Explore → Available

Toxins & Detoxification

Heavy metals, mycotoxins, microplastics, PFAS. IV chelation (EDTA, DMPS, DMSA), IV glutathione, TPE, and functional hepato-renal support. The science of supervised elimination.

Explore → Available

Healing & Post-Operative

The biology of healing. Exosomes, MSC, high-dose IV vitamin C, glutathione, immune modulation, and analgesic peptides applied to post-operative recovery. Complementary to surgical management.

Explore → New

Alzheimer's & Neurodegeneration

The AMBAR Study (Boada et al., Alzheimer's & Dementia 2020): 496 patients, Phase IIb/III, therapeutic plasma exchange with albumin replacement. Peripheral sink hypothesis (DeMattos 2001), amyloid-β clearance, biological plausibility.

Explore → New

ASFA Apheresis Guidelines

American Society for Apheresis — Ninth Special Issue (Connelly-Smith et al., Journal of Clinical Apheresis 2023). 92+ indications classified into four evidence categories (I–IV) and six recommendation grades (1A–2C). The canonical international framework.

Explore → New

Biopolymers, ASIA & Plasma Exchange

ASIA syndrome (Shoenfeld 2011), foreign body modelling reaction, and the role of TPE as a complementary strategy — never a substitute for surgical extraction. Colombian-authored indexed evidence from FUCS-Hospital San José Bogotá (Montealegre, Rojas-Villarraga 2021).

Explore →
Coming soon

Advanced Cardiovascular

ApoB, Lp(a), small dense LDL particles, coronary calcium (CAC), precision lipidomics, early subclinical risk detection.

In production
Coming soon

Microbiome & Gut Health

Gut-brain axis, intestinal permeability, dysbiosis, functional microbiome testing, impact on the immune system.

In production
Coming soon

Metabolism & Body Composition

Insulin resistance, GLP-1 agonists (Semaglutide, Tirzepatide), sarcopenia, visceral fat, metabolically active muscle mass.

In production
Coming soon

Sleep, Hormones & Recovery

Hormonal optimization (testosterone, estrogen, thyroid), deep sleep quality, cortisol and HPA axis, HRV as a recovery metric.

In production
Coming soon

Nutrition & Fasting

Time-restricted eating, intermittent fasting, Mediterranean diet, biomarker-driven supplementation, polyphenols with clinical support.

In production
Coming soon

Exercise for Longevity

Zone 2, VO₂max as a mortality predictor, strength training, functional mobility, and fall prevention in the second half of life.

In production
Coming soon

Stress, Mind & Resilience

Chronic stress, heart rate variability (HRV), meditation, mindfulness, and evidence-based autonomic regulation.

In production
Coming soon

Clinical Studies & Evidence

Curated selection of reference papers: Buck Institute (TPE), Tufts (Achleitner plasmapheresis), MSC trials, peptide and biomarker studies in progress.

In production
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